-
- 所属系：实验中心邮箱：linswallow2015@mail.hfut.edu.cn电话：个人学习工作简介林燕博士2010年毕业于安徽科技学院生物工程专业获得学士学位；2014年5月于合肥工业大学食品科学专业获得硕士学位；2019年12月毕业于合肥工业大学食品科学专业获得博士学位，导师为刘健教授；2020年6月入职合肥工业大学食品与生物工程学院担任实验教师。主要研究领域与方向在秀丽隐杆线虫中建立以葡萄糖和棕榈酸诱导脂肪沉积的模型，研究发现外周溶酶体组织蛋白酶L（CTSL）通过中枢血清素（5-HT）信号，即“外周CTSL-中枢5-HT”环路，调控线虫和小鼠的脂肪沉积；在此基础上研究确定了饮食黄酮类化合物木犀草素通过该环路调控线虫脂肪沉积；并利用该环路建立了降脂天然产物的线虫体内筛选平台。著作论文（代表作）1.YanLin,BinBao,HaoYin,XinWang,AirongFeng,LinZhao,XianqiNie,NanYang,Guo-PingShi,andJianLiu.PeripheralcathepsinLinhibitioninducesf" />
林燕
发布时间：2020-07-08 阅读次数: 1005
 | - 姓 名：
- 林燕
| - 职 称：
实验教师
| - 职 务：
-
| - 所属系：
- 实验中心
| -
- 邮箱：
- linswallow2015@mail.hfut.edu.cn
| -
- 办公地点：
 | - 姓 名：
- 林燕
| - 职 称：
实验教师
| - 职 务：
-
| - 所属系：
- 实验中心
| - 邮 箱：
- linswallow2015@mail.hfut.edu.cn
| - 电 话：
|
个人学习工作简介 林燕博士2010年毕业于安徽科技学院生物工程专业获得学士学位； 2014年5月于合肥工业大学食品科学专业获得硕士学位； 2019年12月毕业于合肥工业大学食品科学专业获得博士学位，导师为刘健教授； 2020年6月入职合肥工业大学食品与生物工程学院担任实验教师。主要研究领域与方向 在秀丽隐杆线虫中建立以葡萄糖和棕榈酸诱导脂肪沉积的模型，研究发现外周溶酶体组织蛋白酶L（CTSL）通过中枢血清素（5-HT）信号，即“外周CTSL-中枢5-HT”环路，调控线虫和小鼠的脂肪沉积；在此基础上研究确定了饮食黄酮类化合物木犀草素通过该环路调控线虫脂肪沉积；并利用该环路建立了降脂天然产物的线虫体内筛选平台。 著作论文（代表作）
1. Yan Lin, Bin Bao, Hao Yin, Xin Wang, Airong Feng, Lin Zhao, Xianqi Nie, Nan Yang, Guo-Ping Shi, and Jian Liu. Peripheral cathepsin L inhibition induces fat loss in C. elegans and mice through promoting central serotonin synthesis [J]. BMC Biology, 2019. 2. Yan Lin, Nan Yang, Bin Bao, Lu Wang, Juan Chen, Jian Liu. Luteolin Reduces Fat Storage in Caenorhabditis elegans through Promoting Central Serotonin Pathway [J]. Food Function, 2020. 3. Zhang X, Wang X, Yin H, Zhang L, Feng A, Zhang QX, Lin Y, Bao B, Hernandez LL, Shi GP, Liu J. Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice [J]. Cell Rep. 2019 Jul 16;28(3):792-803. 4. Na Xu, Yuan-Yuan Zhan, Yan Lin, Bin Bao, Lei Zheng, Guo-Ping Shi, Jian Liu. Increased levels of lysosomal cysteinyl cathepsins in human varicose veins: A histology study [J]. Thromb Haemost. 2014 Feb;111(2):333-44. 5. Bin Bao, Yan-Guang Chen, Lei Zhang, Yan Lin, Na Xu, Xin Wang, Jian Liu, Wei Qu. Momordica charantia (Bitter Melon) Reduces Obesity-Associated Macrophage and Mast Cell Infiltration as well as Inflammatory Cytokine Expression in Adipose Tissues [J]. PLoS ONE 8(12): e84075.
| 职务： |
</dt><dd style="margin:0px;padding:0px;width:335.29px;display:inline-block;"> </dd></dl></td></tr><tr style="margin:0px;padding:0px;border:currentcolor;border-image:none;"><td style="margin:0px;padding:0px;border:currentcolor;word-break:break-all;"><dl style="margin:0px;width:479px;height:auto;color:#666666;line-height:30px;padding-right:0px;padding-left:0px;"><dt style="margin:0px;padding:0px;width:143.68px;text-align:center;font-weight:bold;float:left;display:inline-block;"> |
职称： |
</dt></dl>实验教师<br /><dl><dd></dd></dl></td></tr><tr style="margin:0px;padding:0px;border:currentcolor;border-image:none;"><td style="margin:0px;padding:0px;border:currentcolor;border-image:none;"><dl style="margin:0px;width:479px;height:auto;color:#666666;line-height:30px;padding-right:0px;padding-left:0px;"><dt style="margin:0px;padding:0px;width:143.68px;text-align:center;font-weight:bold;float:left;display:inline-block;"> |
| 所属系： |
实验中心邮箱：linswallow2015@mail.hfut.edu.cn电话：个人学习工作简介林燕博士2010年毕业于安徽科技学院生物工程专业获得学士学位；2014年5月于合肥工业大学食品科学专业获得硕士学位；2019年12月毕业于合肥工业大学食品科学专业获得博士学位，导师为刘健教授；2020年6月入职合肥工业大学食品与生物工程学院担任实验教师。主要研究领域与方向在秀丽隐杆线虫中建立以葡萄糖和棕榈酸诱导脂肪沉积的模型，研究发现外周溶酶体组织蛋白酶L（CTSL）通过中枢血清素（5-HT）信号，即“外周CTSL-中枢5-HT”环路，调控线虫和小鼠的脂肪沉积；在此基础上研究确定了饮食黄酮类化合物木犀草素通过该环路调控线虫脂肪沉积；并利用该环路建立了降脂天然产物的线虫体内筛选平台。著作论文（代表作）1.YanLin,BinBao,HaoYin,XinWang,AirongFeng,LinZhao,XianqiNie,NanYang,Guo-PingShi,andJianLiu.PeripheralcathepsinLinhibitioninducesf" />
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个人学习工作简介 林燕博士2010年毕业于安徽科技学院生物工程专业获得学士学位； 2014年5月于合肥工业大学食品科学专业获得硕士学位； 2019年12月毕业于合肥工业大学食品科学专业获得博士学位，导师为刘健教授； 2020年6月入职合肥工业大学食品与生物工程学院担任实验教师。主要研究领域与方向 在秀丽隐杆线虫中建立以葡萄糖和棕榈酸诱导脂肪沉积的模型，研究发现外周溶酶体组织蛋白酶L（CTSL）通过中枢血清素（5-HT）信号，即“外周CTSL-中枢5-HT”环路，调控线虫和小鼠的脂肪沉积；在此基础上研究确定了饮食黄酮类化合物木犀草素通过该环路调控线虫脂肪沉积；并利用该环路建立了降脂天然产物的线虫体内筛选平台。 著作论文（代表作）
1. Yan Lin, Bin Bao, Hao Yin, Xin Wang, Airong Feng, Lin Zhao, Xianqi Nie, Nan Yang, Guo-Ping Shi, and Jian Liu. Peripheral cathepsin L inhibition induces fat loss in C. elegans and mice through promoting central serotonin synthesis [J]. BMC Biology, 2019. 2. Yan Lin, Nan Yang, Bin Bao, Lu Wang, Juan Chen, Jian Liu. Luteolin Reduces Fat Storage in Caenorhabditis elegans through Promoting Central Serotonin Pathway [J]. Food Function, 2020. 3. Zhang X, Wang X, Yin H, Zhang L, Feng A, Zhang QX, Lin Y, Bao B, Hernandez LL, Shi GP, Liu J. Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice [J]. Cell Rep. 2019 Jul 16;28(3):792-803. 4. Na Xu, Yuan-Yuan Zhan, Yan Lin, Bin Bao, Lei Zheng, Guo-Ping Shi, Jian Liu. Increased levels of lysosomal cysteinyl cathepsins in human varicose veins: A histology study [J]. Thromb Haemost. 2014 Feb;111(2):333-44. 5. Bin Bao, Yan-Guang Chen, Lei Zhang, Yan Lin, Na Xu, Xin Wang, Jian Liu, Wei Qu. Momordica charantia (Bitter Melon) Reduces Obesity-Associated Macrophage and Mast Cell Infiltration as well as Inflammatory Cytokine Expression in Adipose Tissues [J]. PLoS ONE 8(12): e84075.
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