龚德雁-食品与生物工程学院

- 姓名：龚德雁
- 职务：
- 职称：副教授、硕导
- 所属系：药物科学与工程系
- 邮箱：gongdy@hfut.edu.cn
- 办公地点：食品楼410

个人简介
研究领域
科研项目
学术成果
荣誉奖项

2021年1月进入合肥工业大学食品与生物工程学院工作，兰州大学化学化工学院理学博士，美国芝加哥大学化学系联合培养博士（国家留学基金委资助），主要从事纳米药物的生物医学效应及癌症、肝、肠病等重大疾病的成像诊断和治疗研究。主持国家自然科学基金青年项目、安徽省自然科学基金青年项目等多项科研项目，发表高质量论文30余篇。

1.生物成像纳米药剂
2.肝、肠炎症诊断和治疗纳米药剂
3.肿瘤成像诊断和治疗纳米药剂
研究生招生方向：制药工程、药学、生物学、生物技术与工程

1、国家自然科学基金青年项目， 2023.01-2025.12 ，主持，在研
2、安徽省自然科学基金青年项目， 2022.01-2023.12 ，主持，已完成
3、合肥工业大学学术新人提升计划A项目， 2022.05-2023.12，主持，已完成
4、合肥工业大学青年教师科研创新启动专项项目， 2021.05-2023.04，主持，已完成
5、安徽省博士后研究人员科研活动经费资助项目， 2024.10-2025.10，主持，在研
6、国家级大学生创新创业训练计划项目，指导教师；完成
7、省级大学生创新创业训练计划项目，指导教师；在研

代表性论文
1. Xiang Ling#, Deyan Gong#, Wenjie Shi, Ziwan Xu, Wenbo Han, Guangxu Lan, Youyou Li, Wenwu Qin, Wenbin Lin*, Nanoscale Metal−Organic Layers Detect Mitochondrial Dysregulation and Chemoresistance via Ratiometric Sensing of Glutathione and pH, Journal of the American Chemical Society, 2021, 143(3): 1284-1289. （中科院1区TOP 期刊）
2. Deyan Gong, Yuejun Tian, Chengduan Yang, Anam Iqbal, Zhiping Wang, Weisheng Liu, Wenwu Qin*, Xiangtao Zhu, Huichen Guo*, A fluorescence enhancement probe based on BODIPY for the discrimination of cysteine from homocysteine and glutathione [J]. Biosensors and Bioelectronics, 2016, 85, 178-183. （中科院1区TOP 期刊）
3. Deyan Gong, Xiangtao Zhu, Yuejun Tian, Shi-Chong Han, Min Deng, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, A Phenylselenium-Substituted BODIPY Fluorescent Turn-off Probe for Fluorescence Imaging of Hydrogen Sulfide in Living Cells [J]. Analytical Chemistry, 2017, 89, 1801−1807. （中科院1区TOP 期刊）
4. Deyan Gong, Shi-Chong Han, Anam Iqbal, Jing Qian, Ting Cao, Wei Liu, Weisheng Liu, Wenwu Qin*, and Huichen Guo*, Fast and Selective Two-Stage Ratiometric Fluorescent Probes for Imaging of Glutathione in Living Cells [J]. Analytical Chemistry, 2017, 89, 13112−13119. （中科院1区TOP 期刊）
5. Deyan Gong, Ting Cao, Shi-Chong Han, Xiangtao Zhu, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, Fluorescence enhancement thermoresponsive polymer luminescent sensors based on BODIPY for intracellular temperature [J]. Sensors and Actuators B: Chemical, 2017, 252, 577–583. （中科院1区TOP 期刊）
6. Deyan Gong, Jiaxi Ru, Ting Cao, Jing Qian, Wei Liu, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, Two-stage ratiometric fluorescent responsive probe for rapid glutathione detection based on BODIPY thiol-halogen nucleophilic mono- or disubstitution [J]. Sensors and Actuators B: Chemical, 2018, 258, 72–79. （中科院1区TOP 期刊）
7. Deyan Gong#, Xiang Huang#, Zineng Yi, Qianpeng Zhou, Xiaona Xu, Xiaohan Meng, Congyu Liu, Zhaohua Miao, Zhengbao Zha*; Ratiometric fluorescent nanoprobe for imaging and screening of hydrogen sulfide related bacterial resistance [J]. Materials Today Communications, 2022, 32, 103959.
8. Zineng Yi, Xiaona Xu, Xiaohan Meng, Congyu Liu, Qianpeng Zhou, Deyan Gong*, Zhengbao Zha*, Emerging markers for antimicrobial resistance monitoring [J]. Chinese Chemical Letters, 2023, 34(10): 108238.（中科院1区TOP 期刊）
9. Lu Liu, Liu Liu, Yiran Pan, Shiming Wang, Yezi He, Deyan Gong*, Zhengbao Zha*, Multifunctional nanoprobes for the cancer cells pathophysiological processes sensing and imaging [J]. Applied Materials Today, 2024, 36: 102028. （SCI论文）
10. Deyan Gong#, Ziwen Xiao#, Yaoyu Hu, Silong Wu, Zineng Yi, Taikui Sheng, Zhengbao Zha, Yan Ma*, Zhaohua Miao*, Neutrophil elastase-activated carbon dots for non-invasive early diagnosis of inflammatory bowel disease by near-infrared-II fluorescence imaging, Chemical Engineering Journal, 2024, 499: 156099.（中科院1区TOP 期刊SCI论文）
11. Deyan Gong#, Lu Liu#, Ziwen Xiao, Zhuonan Yang, Yaoyu Hu, Taikui Sheng, Yajing Liu, Zhaohua Miao*, Zhengbao Zha*, pH-activated metal–organic layer nanozyme for ferroptosis tumor therapy, Journal of Colloid and Interface Science 680 (2025) 937–947.（中科院1区TOP 期刊SCI论文）
国外英文专著
1. Deyan Gong; Zhengbao Zha*; Chapter 2: Hydroxybenzoic acids, Handbook of Food Bioactive Ingredients. Springer Nature, 2022. ISBN9783030814045.

1.指导本科生获2022年全国大学生生命科学竞赛安徽省三等奖

职务：		职称：	副教授、硕导
所属系：	药物科学与工程系	邮箱：	gongdy@hfut.edu.cn
办公地点：	食品楼410	学术成果	<br>代表性论文 <br>1. Xiang Ling#, Deyan Gong#, Wenjie Shi, Ziwan Xu, Wenbo Han, Guangxu Lan, Youyou Li, Wenwu Qin, Wenbin Lin, Nanoscale Metal−Organic Layers Detect Mitochondrial Dysregulation and Chemoresistance via Ratiometric Sensing of Glutathione and pH, Journal of the American Chemical Society, 2021, 143(3): 1284-1289. （中科院1区TOP 期刊） <br>2. Deyan Gong, Yuejun Tian, Chengduan Yang, Anam Iqbal, Zhiping Wang, Weisheng Liu, Wenwu Qin, Xiangtao Zhu, Huichen Guo, A fluorescence enhancement probe based on BODIPY for the discrimination of cysteine from homocysteine and glutathione [J]. Biosensors and Bioelectronics, 2016, 85, 178-183. （中科院1区TOP 期刊） <br>3. Deyan Gong, Xiangtao Zhu, Yuejun Tian, Shi-Chong Han, Min Deng, Anam Iqbal, Weisheng Liu, Wenwu Qin, Huichen Guo, A Phenylselenium-Substituted BODIPY Fluorescent Turn-off Probe for Fluorescence Imaging of Hydrogen Sulfide in Living Cells [J]. Analytical Chemistry, 2017, 89, 1801−1807. （中科院1区TOP 期刊） <br>4. Deyan Gong, Shi-Chong Han, Anam Iqbal, Jing Qian, Ting Cao, Wei Liu, Weisheng Liu, Wenwu Qin, and Huichen Guo, Fast and Selective Two-Stage Ratiometric Fluorescent Probes for Imaging of Glutathione in Living Cells [J]. Analytical Chemistry, 2017, 89, 13112−13119. （中科院1区TOP 期刊） <br>5. Deyan Gong, Ting Cao, Shi-Chong Han, Xiangtao Zhu, Anam Iqbal, Weisheng Liu, Wenwu Qin, Huichen Guo, Fluorescence enhancement thermoresponsive polymer luminescent sensors based on BODIPY for intracellular temperature [J]. Sensors and Actuators B: Chemical, 2017, 252, 577–583. （中科院1区TOP 期刊） <br>6. Deyan Gong, Jiaxi Ru, Ting Cao, Jing Qian, Wei Liu, Anam Iqbal, Weisheng Liu, Wenwu Qin, Huichen Guo, Two-stage ratiometric fluorescent responsive probe for rapid glutathione detection based on BODIPY thiol-halogen nucleophilic mono- or disubstitution [J]. Sensors and Actuators B: Chemical, 2018, 258, 72–79. （中科院1区TOP 期刊） <br>7. Deyan Gong#, Xiang Huang#, Zineng Yi, Qianpeng Zhou, Xiaona Xu, Xiaohan Meng, Congyu Liu, Zhaohua Miao, Zhengbao Zha; Ratiometric fluorescent nanoprobe for imaging and screening of hydrogen sulfide related bacterial resistance [J]. Materials Today Communications, 2022, 32, 103959. <br>8. Zineng Yi, Xiaona Xu, Xiaohan Meng, Congyu Liu, Qianpeng Zhou, Deyan Gong, Zhengbao Zha, Emerging markers for antimicrobial resistance monitoring [J]. Chinese Chemical Letters, 2023, 34(10): 108238.（中科院1区TOP 期刊） <br>9. Lu Liu, Liu Liu, Yiran Pan, Shiming Wang, Yezi He, Deyan Gong, Zhengbao Zha, Multifunctional nanoprobes for the cancer cells pathophysiological processes sensing and imaging [J]. Applied Materials Today, 2024, 36: 102028. （SCI论文） <br>10. Deyan Gong#, Ziwen Xiao#, Yaoyu Hu, Silong Wu, Zineng Yi, Taikui Sheng, Zhengbao Zha, Yan Ma, Zhaohua Miao, Neutrophil elastase-activated carbon dots for non-invasive early diagnosis of inflammatory bowel disease by near-infrared-II fluorescence imaging, Chemical Engineering Journal, 2024, 499: 156099.（中科院1区TOP 期刊SCI论文） <br>11. Deyan Gong#, Lu Liu#, Ziwen Xiao, Zhuonan Yang, Yaoyu Hu, Taikui Sheng, Yajing Liu, Zhaohua Miao, Zhengbao Zha, pH-activated metal–organic layer nanozyme for ferroptosis tumor therapy, Journal of Colloid and Interface Science 680 (2025) 937–947.（中科院1区TOP 期刊SCI论文） <br>国外英文专著 <br>1. Deyan Gong; Zhengbao Zha*; Chapter 2: Hydroxybenzoic acids, Handbook of Food Bioactive Ingredients. Springer Nature, 2022. ISBN9783030814045.
研究领域	<br>1.生物成像纳米药剂 <br>2.肝、肠炎症诊断和治疗纳米药剂 <br>3.肿瘤成像诊断和治疗纳米药剂 <br>研究生招生方向：制药工程、药学、生物学、生物技术与工程	科研项目	<br>1、国家自然科学基金青年项目， 2023.01-2025.12 ，主持，在研 <br>2、安徽省自然科学基金青年项目， 2022.01-2023.12 ，主持，已完成 <br>3、合肥工业大学学术新人提升计划A项目， 2022.05-2023.12，主持，已完成 <br>4、合肥工业大学青年教师科研创新启动专项项目， 2021.05-2023.04，主持，已完成 <br>5、安徽省博士后研究人员科研活动经费资助项目， 2024.10-2025.10，主持，在研 <br>6、国家级大学生创新创业训练计划项目，指导教师；完成 <br>7、省级大学生创新创业训练计划项目，指导教师；在研
荣誉奖项	<br>1.指导本科生获2022年全国大学生生命科学竞赛安徽省三等奖

药物科学与工程系