杨静文-食品与生物工程学院

- 姓名：杨静文
- 职务：
- 职称：讲师、硕导
- 所属系：药物科学与工程系
- 邮箱：jwyang@hfut.edu.cn
- 办公地点：1112

个人简介
研究领域
科研项目
学术成果
荣誉奖项

学习经历：

2015. 9 -2017.1丹麦奥胡斯大学生物化学工程系联培博士

2011. 9 -2017. 6吉林大学生命科学学院博士

2007.9 -2011.6吉林农业大学农学院本科

工作经历：

2017.7至今合肥工业大学食品与生物工程学院药物科学与工程系讲师

1、基于定向进化的酶的分子改造
2、酶催化及应用

代表性论文
[1] J. Yang*, X. Zhang, Q. Lu, L. Wang, X. Hu, H. Zhang*, Preparation, flocculation and application in sugar refining of eco-friendly dextran-polylysine complex flocculant. Separation and Purification Technology, 2023, 306, 122673.
[2] Y. Zhang, J. Liu, G. Hu, X. Hu, J. Yang*, H. Zhang *, Fusion enzyme design based on the “channelization” cascade theory and homogenous dextran product improvement. International Journal of Biological Macromolecules, 2022, 222, 652–660.
[3] L. Wang, Q. Lu, T. Zeng, J. Yang*, X. Hu, H Zhang*, Synthesis and characterization of a cationic dextran-based flocculant and its application in bacterial sedimentation. Biochemical Engineering Journal, 2022, 185, 108535.
[4] X. Yu, J. Yang*, X. Ding, L Liu, X. Hu, H. Zhang*, Analysis of the Effect of N555 Mutations on the Product Specificity of Dextransucrase Using Caffeic Acid Phenethyl Ester as an Acceptor Substrate. Journal of Agricultural and Food Chemistry, 2021, 69, 5774−5782.
[5] Y. Zhang#, J. Yang#*, X. Yu, X. Hu, H. Zhang*, Engineering Leuconostoc mesenteroides dextransucrase by inserting disulfide bridges for enhanced thermotolerance, Enzyme and Microbial Technology, 2020, 139, 109603.
[6] H. Wu, D. Shangguan, Q. Lu, X. Hu, J. Yang*, H. Zhang*, Oxidation of dextran using H2O2 and NaClO/NaBr and their applicability in iron chelation, International Journal of Biological Macromolecules, 2020, 144, 615-623.
[7] J. Hua, H. Zhang, H. Wu, J. Wang, X. Hu, J. Yang*. Discovery and Characterization of a Novel Method for Effective Improvement of Cyclodextrin Yield and Product Specificity, Chemical Research in Chinese Universities, 2019, 35, 708-713.
[8] M. Li, H. Zhang*, Y. Li, X. Hu, J. Yang*, The thermoduric effects of site-directed mutagenesis of proline and lysine on dextransucrase from Leuconostoc mesenteroides 0326, International Journal of Biological Macromolecules, 2018, 107, 1641~1649.
[9] J. Yang, R. Gao, Y. Zhou, S. Anankanbil, J. Li, G. Xie*, Z. Guo*. β-Glucosidase from Thermotoga naphthophila RKU-10 for exclusive synthesis of galactotrisaccharides: Kinetics and thermodynamics insight into reaction mechanism, Food Chemistry, 2018, 240, 422~429.

职务：		职称：	讲师、硕导
所属系：	药物科学与工程系	邮箱：	jwyang@hfut.edu.cn
办公地点：	1112	学术成果	<br>代表性论文 <br>[1] J. Yang, X. Zhang, Q. Lu, L. Wang, X. Hu, H. Zhang, Preparation, flocculation and application in sugar refining of eco-friendly dextran-polylysine complex flocculant. Separation and Purification Technology, 2023, 306, 122673. <br>[2] Y. Zhang, J. Liu, G. Hu, X. Hu, J. Yang, H. Zhang , Fusion enzyme design based on the “channelization” cascade theory and homogenous dextran product improvement. International Journal of Biological Macromolecules, 2022, 222, 652–660. <br>[3] L. Wang, Q. Lu, T. Zeng, J. Yang, X. Hu, H Zhang, Synthesis and characterization of a cationic dextran-based flocculant and its application in bacterial sedimentation. Biochemical Engineering Journal, 2022, 185, 108535. <br>[4] X. Yu, J. Yang, X. Ding, L Liu, X. Hu, H. Zhang, Analysis of the Effect of N555 Mutations on the Product Specificity of Dextransucrase Using Caffeic Acid Phenethyl Ester as an Acceptor Substrate. Journal of Agricultural and Food Chemistry, 2021, 69, 5774−5782. <br>[5] Y. Zhang#, J. Yang#, X. Yu, X. Hu, H. Zhang, Engineering Leuconostoc mesenteroides dextransucrase by inserting disulfide bridges for enhanced thermotolerance, Enzyme and Microbial Technology, 2020, 139, 109603. <br>[6] H. Wu, D. Shangguan, Q. Lu, X. Hu, J. Yang, H. Zhang, Oxidation of dextran using H2O2 and NaClO/NaBr and their applicability in iron chelation, International Journal of Biological Macromolecules, 2020, 144, 615-623. <br>[7] J. Hua, H. Zhang, H. Wu, J. Wang, X. Hu, J. Yang. Discovery and Characterization of a Novel Method for Effective Improvement of Cyclodextrin Yield and Product Specificity, Chemical Research in Chinese Universities, 2019, 35, 708-713. <br>[8] M. Li, H. Zhang, Y. Li, X. Hu, J. Yang, The thermoduric effects of site-directed mutagenesis of proline and lysine on dextransucrase from Leuconostoc mesenteroides 0326, International Journal of Biological Macromolecules, 2018, 107, 1641~1649. <br>[9] J. Yang, R. Gao, Y. Zhou, S. Anankanbil, J. Li, G. Xie, Z. Guo*. β-Glucosidase from Thermotoga naphthophila RKU-10 for exclusive synthesis of galactotrisaccharides: Kinetics and thermodynamics insight into reaction mechanism, Food Chemistry, 2018, 240, 422~429.
研究领域	<br>1、基于定向进化的酶的分子改造 <br>2、酶催化及应用	科研项目
荣誉奖项