食品生物技术系

1.食品毒理
2.食品营养
3.神经退行性疾病
4.抗衰老机制研究

1.国家自然科学基金青年基金，保幼激素通过Tsf1调控果蝇铁剥夺的机制研究, 2022.01- 2024.12，主持
2.国家重点研发子课题，动物源新食物资源中过敏原精准化脱除技术研究，2023.12-2027.12，主持
3.茶树生物学与资源利用国家重点实验室开放课题：EGCG通过抑制铁死亡改善帕金森病的机制研究, 2021.10-2023.09，主持
4.合肥工业大学学术新人提升计划B，JNK信号通路在铅致肠道损伤中的作用机制研究，2022.04-2023.12，主持
5.青年教师科研创新启动专项A项目，铅暴露影响果蝇生长发育的机制研究，2022.05-2024.05，主持
6.青年教师科研创新启动专项B项目，果蝇保幼激素通过转铁蛋白Tsf1调控生殖的机制研究，2020.05-2022.04，主持

代表性论文
1. Z.H. Liu #, S. Ai#, Y. Xia, and H.L. Wang*, Intestinal toxicity of Pb: Structural and functional damages, effects on distal organs and preventive strategies. Sci Total Environ, 2024. 931: p. 172781.
2. Z.H. Liu#, Y. Xia#, S. Ai, and H.L. Wang, Health risks of Bisphenol-A exposure: From Wnt signaling perspective. Environ Res, 2024. 251(Pt 2): p. 118752.
3. Z.H. Liu*, Y. Zhai, Y. Xia, and Q. Liao, Mating modifies oxidative stress in the brain and confers protection against Parkinson's Disease in a Drosophila model. Biochem Biophys Res Commun, 2024. 737: p. 150911.
4. Z.H. Liu*, Yuyin Zhai, Jiakai Zhang, Wei Huang, Wanrong Li, Wenting Qin, Mitochondrial iron deficiency mediated inhibition of ecdysone synthesis underlies lead (Pb) induced developmental toxicity in Drosophila melanogaster. Toxicol Appl Pharmaco, 2025, 497: 117283
5. Z.H. Liu #; Jin Shang#; Lailai Yan; Tian Wei; Ling Xiang; Hui-Li Wang*; Jigui Cheng; Guiran Xiao*. Oxidative stress caused by lead (Pb) induces iron deficiency in Drosophila melanogaster. Chemosphere, 2020, 243: 125428.
6. Ye, Y.Y., Z.H. Liu*, and H.L. Wang*, Fat body derived juvenile hormone acid methyltransferase functions to maintain iron homeostasis in Drosophila melanogaster. FASEB J, 2024. 38(14): p. e23805.
7. Xia, Y., H. Wang, Z. Xie, Z.H. Liu*, and H.L. Wang*, Inhibition of ferroptosis underlies EGCG mediated protection against Parkinson's disease in a Drosophila model. Free Radic Biol Med, 2024. 211: p. 63-76.
8. Li, D., S. Ai, C. Huang, Z.H. Liu*, and H.L. Wang*, Icariin rescues developmental BPA exposure induced spatial memory deficits in rats. Toxicol Appl Pharmacol, 2024. 482: p. 116776.
9. Guiran Xiao#*, Z.H. Liu#, Mengran Zhao, Hui-Li Wang*, Bing Zhou*. Transferrin 1 traffics iron from the gut and antagonizes the action of ferritin in Drosophila melanogaster. Cell Reports, 2019, 26(3): 748-758.