代表性论文
1. Jiali Liu , Xin Zhang, Zilong Shao, Jingwen Yang * , Hongbin Zhang*(通讯作者), Leucine zipper as a bridge for transaminase self-assembly: A fusion enzyme for efficient chiral conversion of D-phenylglycine, Bioorganic Chemistry ,2024,147:107382.
2. Junzhang Chang, Jingwen Yang, Ben Xing, Xueqin Hu, Changchun Xu, Hongbin Zhang*(通讯作者), Improvement of waste frying oil/cottonseed oil-based biodiesel properties by adjusting unsaturation and its effect on engine emission characteristics, Biochemical Engineering Journal, 2024, 206:109299.
3. Jiali Liu, Xiaojie Ding, Yuanyuan Wu, Xin Zhang, Zilong Shao, Baiza Mir, Zhiwei Li, Jingwen Yang*, Hongbin Zhang*(通讯作者),, Redesigning transamination and decarboxylation characteristics of L-aspartate aminotransferase by site directed mutation of non-active site Molecular Catalysis, 2024,553:113781.
4.Ben Xing, Zhiwei Li, Junzhang Chang, Bingbing Xia, Xueqin Hu, Jingwen Yang*, Hongbin zhang*(通讯作者), Molecular modification based on site-directed mutagenesis improves the substrate specificity of β-ester acyltransferase for L-carnosine synthesis, Process Biochemistry, 2024, 137(2):1-9.
5.Ganpeng Hu, Junyan Luo, Tong Bao, Xueqin Hu, Jingwen Yang*, Hongbin Zhang*(通讯作者)., Rational design of disulfide bonds to improve the thermostability and γ-cyclodextrin production capacity of γ-cyclodextrin glycosyltransferase, Process Biochemistry, 2024, 144(9) :248-255.
6. Zhiwei Li, Chao Hu, Huiyong Chen, Fanping Meng, Baiza Mir, Xueqin Hu, Jingwen Yang * , Hongbin Zhang *(通讯作者)., Rational design of a self-assembly promoting fusion domain enhances high molecular weight levan synthesis by levansucrase SacB, International Journal of Biological Macromolecules , 244 (2023) 125442.
7. jingwen Yang *, Xinyu Zhang, Qimeng Lu , Lei Wang , Xueqin Hu , Hongbin Zhang *(通讯作者). Preparation, flocculation and application in sugar refining of eco-friendly dextran-polylysine complex flocculant, Separation and Purification Technology , 306 (2023) 122673.
8. Yuanyuan Wu, Zhiwei Li , Jingwen Yang*, Yuxin Zhang, Daigang Yang, Jiali Liu, Xiaolong Wei , Xueqin Hu, Hongbin Zhang*(通讯作者),Preparation of lactosucrose catalyzed by levansucrase and evaluation of its prebiotic activity, Process Biochemistry 134 (2023) 76–87.
9. Baiza Mir, Jingwen Yang*, Zhiwei Li, Lei Wang, Vilayat Ali, Xueqin Hu & Hongbin Zhang *(通讯作者),Review on recent advances in the properties, production and applications of microbial dextranases,World Journal of Microbiology and Biotechnology,2023, 39: 242.
10. Wei-Juan Ru, Bing-Bing Xia, Yu-Xin Zhang, Jing-Wen Yang, Hong-Bin Zhang *(通讯作者), Xue-Qin Hu *. Development of thermostable dextranase from Streptococcus mutans (SmdexTM) through in silico design employing B-factor and Cartesian-ΔΔG , Journal of Biotechnology 360 (2022) 142–151.
11.Yuxin Zhang, Jiali Liu, Ganpeng Hu, Xueqin Hu, Jingwen Yang * , Hongbin Zhang *(通讯作者), Fusion enzyme design based on the “channelization” cascade theory and homogenous dextran product improvement, International Journal of Biological Macromolecules, 222 (2022) 652–660.
12. Lei Wanga , Qi-meng Lua, Tao Zenga , Jing-wen Yanga,* , Xue-qin Hua , Hong-bin Zhang a,b,** (通讯作者), Synthesis and characterization of a cationic dextran-based flocculant and its application in bacterial sedimentation, Biochemical Engineering Journal 185 (2022) 108535.
13. Yu-xin Zhang, Jing-wen Yang, Yuan-yuan Wu, Xue-qin Hu *, Hong-bin Zhang *(通讯作者). The stability improvement of dextransucrase by artificial extension modification of the V domain of the enzyme, Enzyme and Microbial Technology , 2021,151:109919.
14. Yu, Xiao-qin; Yang, Jingwen*; Ding, Xiao-jie; Liu, Lanhua; Hu, Xue-Qin; Zhang, Hong-bin*(通讯作者), Analysis of the Effect of N555 Mutations on the Product Specificity of Dextransucrase Using Caffeic Acid Phenethyl Ester as an Acceptor Substrate, Journal of Agricultural and Food Chemistry,2021, 69(20): 5774–5782.
15. YuxinZhang, JingwenYang*, XiaoqinYu, XueqinHu, HongbinZhang*(通讯作者). Engineering Leuconostoc mesenteroides dextransucrase by inserting disulfide bridges for enhanced thermotolerance, Enzyme and Microbial Technology, 2020, 109603 (139):1-7.
16. HaoWu, Ding-cong Shang-guan, Qi-meng Lu, Xue-qin Hu, Jing-wenYang*, Hong-binZhang*(通讯作者). Oxidation of dextran using H2O2 and NaClO/NaBr and their applicability in iron chelation, International Journal of Biological Macromolecules,2020, 144(1): 615-623.
17. TaoZeng, Xue-qinHu*, HaoWu, Jing-wenYang, Hong-binZhang*(通讯作者). Microwave assisted synthesis and characterization of a novel bio-based flocculant from dextran and chitosan, International Journal of Biological Macromolecules, 2019,131 (6) :760–768.
18. Yao Li, Lan-hua Liu*, Xiao-qin Yu, Yu-xin Zhang, Jing-wen Yang, Xue-Qin Hu, Hong-bin Zhang*(通讯作者), Transglycosylation improved caffeic acid phenethyl ester anti-inflammatory activity and water solubility by Leuconostoc mesenteroides dextransucrase, Journal of Agricultural and Food Chemistry, 2019, 67 (16):4505–4512.
19. Shuang Chen, Hao Wu, Jing-han Hua, Jing-wen Yang, Hong-bin Zhang*(通讯作者), Xue-qin Hu* . Effect of NaOH and NaClO/NaBr modification on the structural and physicochemical properties of dextran,New Journal of Chemistry, 2018, 42, 6274 – 6282.
20. Chao Wang, Shuang Chen, Hong-bin Zhang*(通讯作者), Yao Li, Xue-qin Hu. Characterization of the inserted mutagenesis dextransucrases from Leuconostoc mesenteroides 0326 to produce hyperbranched dextran, International Journal of Biological Macromolecules , 2018,112(6): 584–590.
21. Meng-qi Li, Hong-bin Zhang*(通讯作者), Yao Li, Xue-qin Hu, Jing-wen Yang*. The thermoduric effects of site-directed mutagenesis of proline and lysine on dextransucrase from Leuconostoc mesenteroides 0326, International Journal of Biological Macromolecules, 2018, 107(2): 1641-1649.
22. Ruohan Li; Tao Zeng; Min Wu; Hongbin Zhang*(通讯作者); Xueqin Hu*. Effect of esterification on structural, physicochemical and flocculation properties of dextran, Carbohydrate Polymers, 2017, 174: 1129–1137.
23. Chao Wang, Hongbin Zhang*(通讯作者), Mengqi Li, Xueqin Hu. Functional analysis of truncated and site-directed mutagenesis dextransucrases to produce different type dextrans, Enzyme and Microbial Technology, 2017, 102: 26–34.
24.Qiu-ping Li, Chao Wang, Hong-bin Zhang*(通讯作者), Xue-qin Hu, Ruo-han Li, Jing-han Hua. Designing of a novel dextransucrase efficient in synthesizing oligosaccharides, International Journal of Biological Macromolecules, 2017, 95(2) :696–703.
25. Yu-Qi Zhang, Ruo-Han Li, Hong-Bin Zhang*(通讯作者), Xue-Qin Hu . Purification and characterization of a thermostable dextranase from Talaromyces pinophilus and its application to α-glucan degradation, Journal of Industrial Microbiology & Biotechnology, 2017, 44(2): 317–327.
26. Ruo-han Li, Hong-bin Zhang*(通讯作者), Xue-qin Hu, Wei-wei Gan, Qiu-ping Li. An efficiently sustainable dextran-based flocculant: synthesis, characterization and flocculation, Chemosphere, 2016, 159 :342-350.
27. 吴昊, 刘嘉荔, 杨静文, 胡雪芹,张洪斌*, 双酶协同降解胶体几丁质及其作用机制[J]. 食品科学, 2022, 43(6): 74-80.
28. 刘鹏飞,陆启蒙,胡雪芹,侯学文,张洪斌*,α-氨基酸酯酰基转移酶表达纯化、酶学性质及其催化应用研究,生物工程学报,2018, 34(7): 1169−1177.
专利(第一发明人)
1.一种定向合成右旋糖酐的融合酶及其构建方法与应用,专利授权号:ZL 2021 1 0938594.0.
2.一种右旋糖酐-甜菜碱阳离子絮凝剂的制备方法及其应用,专利授权号:ZL 202210546609.3..
3.一种右旋糖酐-聚天冬氨酸阴离子絮凝剂的制备方法及其应用,专利授权号:ZL 2022 1 0466307.5
4.一种右旋糖酐-聚氨基酸阳离子絮凝剂的制备方法及其应用,专利授权号:ZL202110126031.1.
5.一种适合二糖苷转移功能的重组右旋糖酐蔗糖酶大肠杆菌的构建方法,专利授权号:ZL202011238363.0.
6.一种右旋糖酐铁的制备方法,专利授权号:ZL201710615990.3.
7.一种高枝化型右旋糖酐蔗糖酶工程菌的构建方法及其表达应用, 专利授权号:ZL201611136122.9.
8.一种利用混菌发酵制备右旋糖酐蔗糖酶的方法,专利授权号:ZL 201510629290.0.
9.一种嗜松青霉菌株及用该菌株制备右旋糖酐酶的方法,专利授权号: ZL 201410640575.X.
10.一种右旋糖酐酶及其在制备低分子右旋糖酐中的应用,专利授权号:ZL 201410003338.2.
11.制备分子量可控的药用右旋糖酐的方法,专利授权号:ZL 201310247228.6.
12.一种分离纯化粗产品L-α-甘油磷酸胆碱的方法,专利授权号:ZL 201110141032.X.
13.一种重组酶法生产右旋糖酐和果糖的方法, 专利授权号:ZL 201110132305.4.
14.一种哈茨木霉菌株及其用该菌株制备右旋糖酐酶的方法. 专利授权号:ZL 201110117071.6.
15.一种表达右旋糖酐蔗糖酶基因工程菌及其构建方法和用途,专利授权号:ZL 200710134765.4.
著作
1.《药物制剂工程技术与设备》(第三版),化学工业出版社,2019.12,主编;
2.《药物制剂工程技术与设备》(第二版)化学工业出版社,2009.12,主编;
3.《药物制剂工程技术与设备》(第一版)化学工业出版社,2003.8,主编;
4.《制药工程课程设计》,化学工业出版社,主编;
5.《制药工程技术概论》,化学工业出版社出版,参编;