近年来，以第一/通讯（含共同）作者身份在Nat. Synth.、Nat. Chem. Biol.、Chem、Nat. Common.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、CCS Chem.等期刊发表论文20多篇，授权专利3项。
部分已发表学术论文（#：共同/第一作者；*：通讯/共通讯作者）：
1.D. Y. Han#, X. L. Zhu#, G. Y. Deng, W. He, T. Y. Zhang, H. S. Ai*, G. C. Chu*, L. Liu*. Ferricyanide-mediated direct ligation of peptide hydrazides in neutral water. Nat. Synth. 2026, DOI: 10.1038/s44160-026-01121-5.
2.G. C. Chu, L. Liu*. Biomimetic polarity reversal for lysine-targeted bioconjugation. Chem 2026, 12, 102951.
3.T. T. Cui#, N. Liu#, J. Sun, J. J. Li, G. C. Chu*, Y. M. Li*.“Lys-Leu” Motif Empowers Expedient OaAEP1-Catalyzed Generation of N‑Terminal Cysteine Recombinant Proteins for Bioconjugation and Semisynthesis. JACS Au 2026, 6, 943.
4.G. C. Chu, L. Liu*. Protein engineering: Status report. Chapter 9.3: Chemically synthesized proteins. Protein Engineering Design and Selection (40th Anniversary Special Collection). 2026, DOI: 10.1093/protein/gzag020.
5.T. T. Cui#, J. Sun#, N. Liu, B. J. Yu, Y. M. Li*, G. C. Chu*. Chemoselective Azidation of Cysteine Coupled with Traceless Staudinger Ligation Enables Site-Specific Acylation of Recombinant Proteins. Org. Lett. 2026, 28, 6625.
6.F. J. Zhao#, M. Y. Ge#, B. J. Yu, X. N. Han, Y. M. Li*, G. C. Chu*. Acetohydroxamic acid-assisted peptide hydrazide ligation for chemical protein synthesis. Org. Biomol. Chem. 2026, 24, 2061.
7.D. Y. Han#, X. Y. Deng#, Y. Cui#, X. L. Zhu, G. Y. Deng, L. J. Liang, G. C. Chu*, L. Liu*. Superfast Protein Desulfurization Triggered by Low-Energy Visible Light. Angew. Chem. Int. Ed. 2025, e202502884.
8.Y. Wang #, J. Fan #, X. B. Meng #, Q. Y. Shu #, G. C. Chu*, Y. C. Wu, R. Ji, Y. S. Ye, X. W. Wu, J. Shi, H. T. Deng, L. Liu*, Y. M. Li*. Development of nucleus-targeted histone-tail-based photoaffinity probes to profile the epigenetic interactome in native cells. Nat. Common. 2025, 16(1): 415.
9.Q. Shi #, Z. H. Deng #, L. Y. Zhang #, Z. B. Tong, J. B. Li, G. C. Chu*, H. S. Ai*, L. Liu*. Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally Defined K63-Polyubiquitylated Linker Histone H1. Angew. Chem. Int. Ed. 2025, 64, e202413651.
10.G. C. Chu, Y. M. Li*. Lighting up kinase contacts in situ. Nat. Chem. Biol. 2024, 20, 544-545.
11.T. Y. Wang, W. W. Shi, G. C. Chu*, Y. M. Li*. Efficient Chemical Synthesis and Folding of Mirror-Image Tropomyosin Receptor Kinase A Using the Strategy of Removable Glycosylation Modification. Chin. J. Chem. 2024, 42, 2316-2322.
12.G. C. Chu #, L. J. Liang #, R. Zhao #, Y. Y. Guo, C. T. Li, C. Zuo, H. S. Ai, X. Hua, Z. C. Li, Y. M. Li, L. Liu*. Ferricyanide-promoted Oxidative Activation and Ligation of Protein Thioacids in Neutral Aqueous Media. CCS Chem. 2024, 6, 2031-2043.
13.H. S. Ai #, G. C. Chu #, Q. Y. Gong #, Z. H. Deng, Z. B. Tong, X. Liu, F. Yan, J. B. Li*, C. L. T*, L. Liu*. Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes. J. Am. Chem. Soc. 2022, 144, 18329-18337.
14.L. J. Liang #, G. C. Chu #, Q. Qu #, C. Zuo, J. X. Mao, Q. Y. Zheng, J. N. Chen, X. B. Meng, Y. W. Jing, H. T. Deng, Y. M. Li, L. Liu*. Chemical Synthesis of Activity-Based E2-Ubiquitin Probes for the Structural Analysis of E3 Ligase-Catalyzed Transthiolation. Angew. Chem. Int. Ed. 2021, 60, 17171-17177.
15.G. C. Chu #, M. Pan #, J. B. Li #, S. L. Liu, C. Zuo, Z. B. Tong, J. S. Bai, Q. Y. Gong, H. S. Ai, J. Fan, X. B. Meng, Y. C. Huang, J. Shi, H. T. Deng, C. L. Tian*, Y. M. Li*, L. Liu*. Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones. J. Am. Chem. Soc. 2019, 141, 3654-3663.
16.B. C. Zhang #, Y. P. Zheng #, G. C. Chu #, X. Y. Deng, T. Y. Wang, W. W. Shi, Y. K. Zhou, S. Tang, J. S. Zheng, L. Liu*. Backbone-Installed Split Intein-Assisted Ligation for the Chemical Synthesis of Mirror-Image Proteins. Angew. Chem. Int. Ed. 2023, 62, e202306270.
17.Q. Y. Zheng #, T. Wang #, G. C. Chu #, C. Zuo, R. Zhao, X. Sui, L. Z Ye, Y. Y. Yu, J. N. Chen, X. W. Wu, W. H. Zhang, H. T. Deng, J. Shi, M. Pan*, Y. M. Li*, L. Liu*. Isopeptide-N-ethylated deubiquitylase-resistant ubiquitin probes made through an E1-catalyzed chemoenzymatic strategy. Angew. Chem. Int. Ed. 2020, 59, 13496-13501.
