硕士生导师

    • 姓名:龚德雁
    • 职务:
    • 职称:副教授、硕导
    • 所属系:药物科学与工程系
    • 邮箱:gongdy@hfut.edu.cn
    • 办公地点:食品楼410
  • 个人简介
  • 研究领域
  • 科研项目
  • 学术成果
  • 荣誉奖项

2021年1月进入合肥工业大学食品与生物工程学院工作,兰州大学化学化工学院理学博士,美国芝加哥大学化学系联合培养博士(国家留学基金委资助),国家自然科学基金函评专家。主要从事纳米药物的生物医学效应及肝、肠病、癌症等重大疾病的成像诊断和治疗研究。主持国家自然科学基金青年项目、安徽省自然科学基金青年项目等多项科研项目,发表高质量论文30余篇,授权中国发明专利多项。

职务: 职称: 副教授、硕导
所属系: 药物科学与工程系 邮箱: gongdy@hfut.edu.cn
办公地点: 食品楼410 学术成果 <br>代表性论文
<br>1.Xiang Ling#, Deyan Gong#, Wenjie Shi, Ziwan Xu, Wenbo Han, Guangxu Lan, Youyou Li, Wenwu Qin, Wenbin Lin*, Nanoscale Metal−Organic Layers Detect Mitochondrial Dysregulation and Chemoresistance via Ratiometric Sensing of Glutathione and pH, Journal of the American Chemical Society, 2021, 143(3): 1284-1289. (中科院1区TOP 期刊)
<br>2.Deyan Gong, Yuejun Tian, Chengduan Yang, Anam Iqbal, Zhiping Wang, Weisheng Liu, Wenwu Qin*, Xiangtao Zhu, Huichen Guo*, A fluorescence enhancement probe based on BODIPY for the discrimination of cysteine from homocysteine and glutathione [J]. Biosensors and Bioelectronics, 2016, 85, 178-183. (中科院1区TOP 期刊)
<br>3.Deyan Gong, Xiangtao Zhu, Yuejun Tian, Shi-Chong Han, Min Deng, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, A Phenylselenium-Substituted BODIPY Fluorescent Turn-off Probe for Fluorescence Imaging of Hydrogen Sulfide in Living Cells [J]. Analytical Chemistry, 2017, 89, 1801−1807. (中科院1区TOP 期刊)
<br>4.Deyan Gong, Shi-Chong Han, Anam Iqbal, Jing Qian, Ting Cao, Wei Liu, Weisheng Liu, Wenwu Qin*, and Huichen Guo*, Fast and Selective Two-Stage Ratiometric Fluorescent Probes for Imaging of Glutathione in Living Cells [J]. Analytical Chemistry, 2017, 89, 13112−13119. (中科院1区TOP 期刊)
<br>5. Deyan Gong, Ting Cao, Shi-Chong Han, Xiangtao Zhu, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, Fluorescence enhancement thermoresponsive polymer luminescent sensors based on BODIPY for intracellular temperature [J]. Sensors and Actuators B: Chemical, 2017, 252, 577–583. (中科院1区TOP 期刊)
<br>6.Deyan Gong, Jiaxi Ru, Ting Cao, Jing Qian, Wei Liu, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, Two-stage ratiometric fluorescent responsive probe for rapid glutathione detection based on BODIPY thiol-halogen nucleophilic mono- or disubstitution [J]. Sensors and Actuators B: Chemical, 2018, 258, 72–79. (中科院1区TOP 期刊)
<br>7.Zineng Yi, Xiaona Xu, Xiaohan Meng, Congyu Liu, Qianpeng Zhou, Deyan Gong*, Zhengbao Zha*, Emerging markers for antimicrobial resistance monitoring [J]. Chinese Chemical Letters, 2023, 34(10): 108238.(中科院1区TOP 期刊)  
<br>8.Deyan Gong#, Ziwen Xiao#, Yaoyu Hu, Silong Wu, Zineng Yi, Taikui Sheng, Zhengbao Zha, Yan Ma*, Zhaohua Miao*, Neutrophil elastase-activated carbon dots for non-invasive early diagnosis of inflammatory bowel disease by near-infrared-II fluorescence imaging, Chemical Engineering Journal, 2024, 499: 156099.(中科院1区TOP 期刊SCI论文)
<br>9.Deyan Gong#, Lu Liu#, Ziwen Xiao, Zhuonan Yang, Yaoyu Hu, Taikui Sheng, Yajing Liu*, Zhaohua Miao*, Zhengbao Zha*, pH-activated metal–organic layer nanozyme for ferroptosis tumor therapy, Journal of Colloid and Interface Science 680 (2025) 937–947.(中科院1区TOP 期刊SCI论文)
<br>10.Ziwen Xiao, Yu Liu, Zhenchao Tao, Yu Zhang, Qian Chen, Zhaohua Miao, Zhengbao Zha, Yan Ma*, Hua Wang*, Deyan Gong*. Tungsten disulfide atomic crystals with RONS scavenging and liver targeting capabilities for acetaminophen-induced acute liver injury therapy. Journal of Nanobiotechnology 23, 665 (2025).(中科院1区TOP 期刊SCI论文)
<br>11.Yu Liu, Ziwen Xiao, Yu Zhang, Qian Chen, Siyu Luo, Yaoqing Wang, Zhaohua Miao, Zhenchao Tao*, Deyan Gong*, Polypyrrole nanozymes with cell-free DNA scavenging and ferroptosis inhibition capabilities for the treatment of acetaminophen-induced acute liver injury,     Acta Biomaterialia, 215 (2026) 215-227.(中科院1区TOP 期刊SCI论文)
<br>国外英文专著
<br>1.Deyan Gong; Zhengbao Zha*; Chapter 2: Hydroxybenzoic acids, Handbook of Food Bioactive Ingredients. Springer Nature, 2022. ISBN9783030814045.
<br>专利
<br>1.中性粒细胞弹性蛋白酶激活型近红外二区荧光碳点及其在炎症性肠病诊断中的应用,中国授权专利,ZL 2024 1 0967881.8
<br>2.一种聚赖氨酸修饰的钨基杂多酸纳米簇及其应用,中国授权专利,2025117046829
研究领域 <br>1.肝、肠炎症诊断和治疗纳米药剂
<br>2.生物成像纳米药剂
<br>3.肿瘤成像诊断和治疗纳米药剂
<br>研究生招生方向:制药工程、药学、生物学、生物技术与工程
科研项目 <br>1、国家自然科学基金青年项目, 2023.01-2025.12 ,主持,已完成
<br>2、安徽省自然科学基金青年项目, 2022.01-2023.12 ,主持,已完成
<br>3、合肥工业大学学术新人提升计划B项目, 主持
<br>4、合肥工业大学学术新人提升计划A项目, 主持
<br>5、安徽省博士后研究人员科研活动经费资助项目, 主持,已完成
<br>6、国家级大学生创新创业训练计划项目,指导教师;完成
<br>7、省级大学生创新创业训练计划项目,指导教师;在研
荣誉奖项 <br>1.指导本科生获全国大学生生命科学竞赛安徽省二等奖、三等奖
<br>2.指导硕士肖紫文荣获硕士研究生国家奖学金、安徽省优秀毕业生

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