食品生物技术系

1.园艺作物成熟衰老相关基因的功能研究
（1）以番茄等园艺作物为材料，利用转基因技术、基因编辑技术，从分子水平解析成熟衰老相关基因的作用机制；
（2）解析硫化氢、乙烯等信号分子对果蔬采后衰老的调控作用。
2.果蔬采后储藏过程中的衰老机制解析
（1）解析果蔬采后衰老的生物学基础；
（2）解析硫化氢、乙烯等信号分子对果蔬采后衰老的调控作用。

1. 国家自然科学基金面上项目：半胱氨酸脱巯基酶LCD调控番茄果实成熟衰老的机制研究(项目号31970200)，2020.01-2023.12，主持人。
2. 安徽省科技攻关项目：大豆磷脂精深加工技术开发及高值化功能磷脂产品的产业化应用，2024.09-2026.12，主持人。
3. 合肥工业大学优秀青年人才培育计划A项目：植物中巯基化修饰蛋白的鉴定及功能研究(项目号JZ2021HGPA0063)，2021.05-2023.12，主持人。
4. 合肥工业大学应用培育计划项目：番茄病虫害防治及优质高产技术开发(项目号JZ2020YYPY0249)，2020.06-2021.06，主持人。
5. 安徽元创科技有限公司横向课题：大豆磷脂提取工艺及磷脂产品技术开发(项目号W2020JSKF0843)，2020.12-2021.12，主持人。
6. 安庆市中创工程技术有限责任公司横向课题：功能性磷脂合成的关键技术及其生理功能研究(项目号W2020JSFW0483)，2020.12-2021.12，主持人。
7. 江苏徐淮地区徐州农业科学研究所横向课题：甘薯叶片抗衰老性与其耐贮性相关分析及快捷鉴定技术(项目号W2020JSKF0842)，2018.05-2019.12，主持人。
8. 中央高校基本科研业务费学术新人B项目：半胱氨酸脱巯基酶LCD调控番茄果实成熟衰老的机制研究(项目号JZ2018HGTB0241)，2018.5-2019.12，主持人。
9. “国家甘薯产业技术体系建设”子课题：耐储藏甘薯资源的筛选与鉴定(项目号CARS-11-B-02)，2011.01-2020.12，主持人。
10. 国家自然科学基金项目：蛋白磷酸酶去活化cAMP通路调控白色念珠菌形态转变的机制研究(项目号31300133)，2014.01-2016.12，主持人。

代表性论文
1.Ying Sun, Min Zhang, Menghui Geng, Zhikun Geng, Zixu Lu, Nannan Liu,Zhanmin Liu, Dexin Zeng, Gaifang Yao, Kangdi Hu*(通讯作者), Hua Zhang*(通讯作者). Hydrogen sulfide interferes with ethylene biosynthesis and signaling pathway in tomato by the mediation of SlERF.D2 persulfidation. Plant Journal. 2025, 121(4) DOI: 10.1111/tpj.70000
2.Kangdi Hu†,*(通讯作者), Meihui Geng†, Lin Ma†, Gaifang Yao, Min Zhang, Hua Zhang*(通讯作者). H2S-responsive ERF.D3 regulates tomato leaf senescence and fruit ripening by modulating abscisic acid metabolism. Plant Physiology, 2025, 197(2)
3.Min Zhang, Kangdi Hu*(通讯作者), Lin Ma, Meihui Geng, Conghe Zhang, Gaifang Yao, and Hua Zhang*(通讯作者). Persulfidation and phosphorylation of transcription factor SlWRKY6 differentially regulate tomato fruit ripening. Plant Physiology, 2024, 196(1), 210–227. DOI:10.1093/plphys/kiae271
4. Yu-Qi Zhao#, Kang-Di Hu#*(通讯作者), Gai-Fang Yao, Si-Yue Wang, Xiang-Jun Peng, Hua Zhang*(通讯作者). A D-cysteine desulfhydrase, SlDCD2, participates in tomato fruit ripening by modulating ROS homoeostasis and ethylene biosynthesis. Horticulture Research. 2023, 10(3), uhad014.
5.Kangdi Hu#(通讯作者), Xiangjun Peng#, Gaifang Yao, Zhilin Zhou, Feng Yang, Wanjie Li, Yuqi Zhao, Yanhong Li, Zhuo Han, Xiaoyan Chen, Hua Zhang*(通讯作者). Roles of a cysteine desulfhydrase LCD1 in regulating leaf senescence in tomato. International Journal of Molecular Sciences. 2021, 22: 13078.
6.Li-Xia Li#, Zeng-Zheng Wei#, Zhi-Lin Zhou#, Dong-Lan Zhao, Jun Tang, Feng Yang, Yan-Hong Li, Xiao-Yan Chen, Zhuo Han, Gai-Fang Yao*(通讯作者), Kang-Di Hu*(通讯作者), Hua Zhang*(通讯作者). A single amino acid mutant in the EAR motif of IbMYB44.2 reduced the inhibition of anthocyanin accumulation in the purple-fleshed sweetpotato. Plant Physiology and Biochemistry. 2021, 167: 410-419.
7.Kang-Di Hu#, Xiao-Yue Zhang#, Gai-Fang Yao#, Yu-Lei Rong, Chen Ding, Jun Tang, Feng Yang, Zhong-Qin Huang, Zi-Mu Xu, Xiao-Yan Chen, Yn-Hong Li, Lan-Ying Hu, Hua Zhang*(通讯作者). A nuclear-localized cysteine desulfhydrase plays a role in fruit ripening in tomato. Horticulture Research. 2020, 7(1): 211.
8.Gai-Fang Yao#, Zeng-Zheng Wei#, Ting-Ting Li#, Jun Tang, Zhong-Qin Huang, Feng Yang, Yan-Hong Li, Zhuo Han, Fan Hu, Lan-Ying Hu, Kang-Di Hu*(通讯作者), Hua Zhang*(通讯作者). Modulation of enhanced antioxidant activity by hydrogen sulfide antagonizing ethylene in tomato fruit ripening. Journal of Agricultural and Food Chemistry. 2018, 66(40):10380-10387.
9.Shi-Ping Li#, Kang-Di Hu#, Lan-Ying Hu, Yan-Hong Li, An-Min Jiang, Fang Xiao, Yi Han, Yong-Sheng Liu, Hua Zhang*(通讯作者). Hydrogen sulfide alleviates postharvest senescence of broccoli by modulating antioxidant defense and senescence-related gene expression. Journal of Agricultural and Food Chemistry. 2014, 62(5): 1119-1129.
10.Kang-Di Hu#, Xiao-Yue Zhang#, Sha-Sha Wang, Jun Tang, Feng Yang, Zhong-Qin Huang, Jing-Yu Deng, Si-Yuan Liu, Shang-Jun Zhao, Lan-Ying Hu, Gai-Fang Yao*(通讯作者), Hua Zhang*(通讯作者). Hydrogen sulfide inhibits fruit softening by regulating ethylene synthesis and signaling pathway in tomato (Solanum lycopersicum). HortScience, 2019, 54 (10), 1824-1830.
11.Shang-Xuan Guo#, Gai-Fang Yao#, Hui-Ran Ye#, Jun Tang, Zhong-Qin Huang, Feng Yang, Yan-Hong Li, Zhuo Han, Lan-Ying Hu, Hua Zhang*(通讯作者), Kang-Di Hu*(通讯作者). Functional Characterization of a Cystathionine β-Synthase Gene in Sulfur Metabolism and Pathogenicity of Aspergillus niger in Pear Fruit. Journal of Agricultural and Food Chemistry. 2019, 67 (16): 4435-4443.
12.Gai-Fang Yao#, Zeng-Zheng Wei#, Ting-Ting Li#, Jun Tang, Zhong-Qin Huang, Feng Yang, Yan-Hong Li, Zhuo Han, Fan Hu, Lan-Ying Hu, Kang-Di Hu*(通讯作者), Hua Zhang*(通讯作者). Modulation of enhanced antioxidant activity by hydrogen sulfide antagonizing ethylene in tomato fruit ripening. Journal of Agricultural and Food Chemistry. 2018, 66(40):10380-10387.
13.Kang-Di Hu#, Gui-Sheng Bai, Wan-Jie Li, Hong Yan, Lan-Ying Hu, Yan-Hong Li, Hua Zhang*(通讯作者). Sulfur dioxide promotes germination and plays an antioxidant role in cadmium stressed wheat seeds. Plant Growth Regulation. 2015, 75 (1): 271-280.
专利
1.一种促进花青苷合成的PyWRKY31基因及其重组表达载体与应用，专利授权号：201911385943.X.
2.一种促进番茄果实成熟的基因及其调控方法. 专利申请号：202210850569.1

1. 2019年度新疆维吾尔自治区科学技术奖二等奖,甘薯优良品种评价利用及配套栽培 技术集成应用。
2. 担任Plant Hormones青年编委，担任Journal of Experimental Botany、Postharvest Biology and Technology 杂志审稿人。