食品质量与安全系

1.功能性核酸的体外筛选及应用研究
2.生物传感器的构建及在生物医学与食品安全检测中的应用

1.国家自然科学基金面上项目，32572680，2026.01-2029.12，主持。
2.国家自然科学基金青年项目，22104028，2022.01-2024.12，主持。
3.国家重点研发计划项目子课题，2020YFC1606802，2021.01-2022.12，主持。
4.安徽省自然科学基金青年项目，2108085QC139，2021.01-2022.12，主持。
5.合肥工业大学学术人才自主创新项目，JZ2025HGTG0262，2025.04-2026.12，主持。
6.合肥工业大学学术新人提升计划B项目，JZ2023HGTB0229，2023.04-2024.12，主持。
7.合肥工业大学学术新人提升计划A项目，JZ2021HGTA0172，2021.04-2022.12，主持。
8.横向项目，W2020JSFW0384，2020.05-2020.12，主持。
9.中央高校专项资助基金，JZ2019HGBH0196，2019.01-2020.12，主持。
10.中国博士后科学基金面上项目，2018M642510，2018.12-2019.11，主持。

代表性论文
1. Yuefei Zhou Lili Yao, Hao Qu, Yu Mao*, Lei Zheng*. Direct evolution of matrix-resistant circular bivalent DNA aptamers for Ara h1. Analytical Chemistry, 2025, 97, 6277. (共同通讯作者)
2. Lili Yao, Tao Liu, Long Sun, Shengjie Gao, Shuai Liu, Hao Qu, Yu Mao*, Lei Zheng*. Selection of high-affinity and selectivity AFB1 circular aptamer for biosensor application. Journal of Agricultural and Food Chemistry, 2025, 73, 3222. (共同通讯作者)
3. Lei Wang, Sipeng Yu, Ju Wang, Qiuping Wang, Yu Mao*, Lei Zheng*. Manganese-doped carbon nanospheres with robust peroxidase-like activity for the colorimetric detection of total antioxidant capacity. Food Chemistry, 2025, 484, 144349. (共同通讯作者)
4. Jie Wang, Yuefei Zhou, Long Sun, Tao Liu, Hao Qu, Yu Mao*, Lei Zheng*. Binding-site directed selection and large-scale click-synthesis of a coagulation factor XIa-inhibiting circular DNA aptamer. Chemistry-A European Journal, 2025, 31, e202404372. (共同通讯作者)
5. Lili Yao†, Junmei Feng†, Yuefei Zhou, Shengjie Gao, Shuai Liu, Hao Qu, Yu Mao*, Lei Zheng*. Single-round circular aptamer discovery using bioinspired magnetosome-like magnetic chain cross-linked graphene oxide. Research, 2024, 7, 0372. (共同通讯作者)
6. Lili Yao, Lei Wang, Shuai Liu, Hao Qu, Yu Mao*, Yingfu Li*, Lei Zheng*. Evolution of a bispecific G-quadruplex-forming circular aptamer to block IL-6/sIL-6R interaction for inflammation inhibition. Chemical Science, 2024, 15, 13011. (共同通讯作者)
7. Lei Wang, Zixuan Liu, Lili Yao, Shuai Liu, Qiuping Wang, Hao Qu, Yuen Wu, Yu Mao*, Lei Zheng*. A bioinspired single-atom Fe nanozyme with excellent laccase-like activity for efficient aflatoxin B1 removal. Small, 2024, 20, e2400629. (共同通讯作者)
8. Yu Mao, Shengjie Gao, Lili Yao, Lei Wang, Hao Qu*, Yuen Wu, Ying Chen, Lei Zheng*. Single-atom nanozyme enabled fast and highly sensitive colorimetric detection of Cr(VI). Journal of Hazardous Materials, 2021, 408, 124898. (第一作者，高倍引，引用150次)
9. Yu Mao, Jimmy Gu, Dingran Chang, Lei Wang, Lili Yao, Qihui Ma, Zhaofeng Luo, Hao Qu, Yingfu Li*, Lei Zheng*. Evolution of a highly functional circular DNA aptamer in serum. Nucleic Acids Research, 2020, 48, 10681. (第一作者)
10. Yu Mao, Meng Liu, Kha Tram, Jimmy Gu, B. J Salena, Yuyang Jiang* and Yingfu Li*. Optimal DNA templates for rolling circle amplification revealed by in vitro selection. Chemistry-A European Journal, 2015, 21, 8069. (第一作者)
授权专利
1.THROMBIN BINDING CIRCULAR APTAMER AND USE THEREOF，专利授权号：US 12,365,904 B2
2.一种IL-6/sIL-6R双特异性环状核酸适配体及试剂盒与应用，专利授权号：ZL202211335410.2.
3.凝血酶环状核酸适配体及其应用，专利授权号：ZL201910595164.6.
4.循环microRNAs检测试剂盒和特异性检测循环microRNAs的方法及应用，专利授权号：ZL201811360587.1.
5.双向信号扩增检测miRNA的试剂盒及方法，专利授权号：ZL201710149371.X.
6.ATP核酸适配体、利用纳米金显色检测ATP的方法及试剂盒，专利授权号：ZL201710124724.0.
7.一种检测黄曲霉毒素B1的方法，专利授权号：ZL201610020877.6.