代表性论文:
1.Xinyan Mao, Hongbin Zhang, Chao Hu, Chunhui Ma, Xueqin Hu, Jingwen Yang*, Rational Engineering of Cellobiose 2-Epimerase Through Flexible Loop Modulation and Structure-Guided Sequence Alignment for Enhanced Lactulose Synthesis, Biomolecules, (2026) 16: 206
2.Junzhang Chang, Yuxin Zhang, Ben Xing, Zifan Ye, Jingwen Yang*, Hongbin Zhang*, Semirational Design of Methanol-Resistant Lipase Mutants: A Pathway to Efficient Biodiesel Production, Journal of Agricultural and Food Chemistry, (2025)73: 7877−7887
3.Zhiwei Li, Tong Bao, Kaiwen Chen, Chao Hu, Xinyu Zhang, Xueqin Hu, Jingwen Yang*, Hongbin Zhang*, Tailoring of levansucrase product size by a comparative molecular dynamics approach, Enzyme and Microbial Technology, (2025) 184:110577
4.Lei Wang#, Xinyu Zhang#, Xin Zhang, Xueqin Hu, Jingwen Yang*, Hongbin Zhang*, Mechanism analysis of a novel natural cationic modified dextran flocculant and its application in the treatment of blue algal blooms, International Journal of Biological Macromolecules, (2024) 254: 128002.
5.Xinyu Zhang, Yuxin Zhang, Zifan Ye, Yuanyuan Wu, Baohong Cai, Jingwen Yang*, Temperature-regulated cascade reaction for homogeneous oligo-dextran synthesis using a fusion enzyme, International Journal of Biological Macromolecules, (2024) 278: 136195.
6.Jiali Liu, Xin Zhang, Zilong Shao, Jingwen Yang*, Hongbin Zhang*, Leucine zipper as a bridge for transaminase self-assembly: A fusion enzyme for efficient chiral conversion of d-phenylglycine, Bioorganic Chemistry, (2024) 147: 107382.
7.Jiali Liu, Xiaojie Ding, Yuanyuan Wu, Xin Zhang, Zilong Shao, Baiza Mir, Zhiwei Li, Jingwen Yang*, Hongbin Zhang*, Redesigning transamination and decarboxylation characteristics of L-aspartate aminotransferase by site directed mutation of non-active site, Molecular Catalysis, (2024) 553: 113781.
8.Ganpeng Hu, Junyan Luo, Tong Bao, Xueqin Hu, Jingwen Yang*, Hongbin Zhang*, Rational design of disulfide bonds to improve the thermostability and γ-cyclodextrin production capacity of γ-cyclodextrin glycosyltransferase, Process Biochemistry, (2024) 144: 248-255.
9.Ben Xing, Zhiwei Li, Junzhang Chang, Bingbing Xia, Xueqin Hu, Jingwen Yang*, Hongbin Zhang*, Molecular modification based on site-directed mutagenesis improves the substrate specificity of β-ester acyltransferase for L-carnosine synthesis, Process Biochemistry, (2024) 137: 1-9.
10.Junzhang Chang, Yuxin Zhang, Zhiwei Li, Yunfeng Ma, Xueqin Hu, Jingwen Yang*, Hongbin Zhang*, Biosynthesis of α-keto acids and resolution of chiral amino acids by l-amino acid deaminases from Proteus mirabilis, Protein Expression and Purification, (2024) 221: 106518.
11.Jingwen Yang*, Xinyu Zhang, Qimeng Lu, Lei Wang, Xueqin Hu, Hongbin Zhang*, Preparation, flocculation and application in sugar refining of eco-friendly dextran-polylysine complex flocculant. Separation and Purification Technology, (2023) 306: 122673.
12.Zhiwei Li, Chao Hu, Huiyong Chen, Fanping Meng, Baiza Mir, Xueqin Hu, Jingwen Yang*, Hongbin Zhang*, Rational design of a self-assembly promoting fusion domain enhances high molecular weight levan synthesis by levansucrase SacB. International Journal of Biological Macromolecules, (2023) 244: 125442.
13.Baiza Mir, Jingwen Yang*, Zhiwei Li, Lei Wang, Vilayat Ali, Xueqin Hu, Hongbin Zhang*, Review on recent advances in the properties, production and applications of microbial dextranases, World Journal of Microbiology and Biotechnology, (2023) 39:242.
14.Yuanyuan Wu, Zhiwei Li, Jingwen Yang*, Yuxin Zhang, Daigang Yang, Jiali Liu, Xiaolong Wei, Xueqin Hu, Hongbin Zhang*, Preparation of lactosucrose catalyzed by levansucrase and evaluation of its prebiotic activity, Process Biochemistry, (2023) 134: 76–87.
15.Yuxin Zhang, Jiali Liu, Ganpeng Hu, Xueqin Hu, Jingwen Yang*, Hongbin Zhang*, Fusion enzyme design based on the “channelization” cascade theory and homogenous dextran product improvement, International Journal of Biological Macromolecules, (2022) 222: 652–660.
16.Lei Wang, Qimeng Lu, Tao Zeng, Jingwen Yang*, Xueqin Hu, Hongbin Zhang*, Synthesis and characterization of a cationic dextran-based flocculant and its application in bacterial sedimentation, Biochemical Engineering Journal, (2022) 185: 108535.
17.Xiaoqin Yu, Jingwen Yang*, Xiaojie Ding, Lanhua Liu, Xueqin Hu, Hongbin Zhang*, Analysis of the Effect of N555 Mutations on the Product Specificity of Dextransucrase Using Caffeic Acid Phenethyl Ester as an Acceptor Substrate, Journal of Agricultural and Food Chemistry, (2021) 69: 5774−5782.
18.Yuxin Zhang#, JingwenYang#*, Xiaoqin Yu, Xueqin Hu, Hongbin Zhang*, Engineering Leuconostoc mesenteroides dextransucrase by inserting disulfide bridges for enhanced thermotolerance, Enzyme and Microbial Technology, (2020)139: 109603.
19.Hao Wu, Dingcong Shangguan, Qimeng Lu; Xueqin Hu; Jingwen Yang*; Hongbin Zhang*, Oxidation of dextran using H2O2 and NaClO/NaBr and their applicability in iron chelation, International Journal of Biological Macromolecules, (2020) 144: 615-623.
20.Jinghan Hua, Hongbin Zhang, Hao Wu, Jiadong Wang, Xueqin Hu, Jingwen Yang*, Discovery and Characterization of a Novel Method for Effective Improvement of Cyclodextrin Yield and Product Specificity, Chemical Research in Chinese Universities, (2019) 35: 708-713.
21.Mengqi Li, Hongbin Zhang*, Yao Li, Xueqin Hu, Jingwen Yang*, The thermoduric effects of site-directed mutagenesis of proline and lysine on dextransucrase from Leuconostoc mesenteroides 0326, International Journal of Biological Macromolecules, (2018) 107: 1641-1649.
22.Jingwen Yang, Renjun Gao, Ye Zhou, Sampson Anankanbil, Jingbo Li, Guiqiu Xie*, Zheng Guo*, β-Glucosidase from Thermotoga naphthophila RKU-10 for exclusive synthesis of galactotrisaccharides: Kinetics and thermodynamics insight into reaction mechanism, Food Chemistry, (2018) 240: 422-429.
23.Jingwen Yang, Qi Wang, Ye Zhou, Jingbo Li, Renjun Gao*, Zheng Guo*, Engineering T. naphthophila β-glucosidase for enhanced synthesis of galactooligosaccharides by site-directed mutagenesis, Biochemical Engineering Journal, (2017) 127: 1-8.
24.Jingwen Yang, Bianca Pérez, Sampson Anankanbil, Jingbo Li, Ye Zhou, Renjun Gao*, Zheng Guo*, Valorizing Dairy Waste: Thermophilic Biosynthesis of a Novel Ascorbic Acid Derivative, Journal of Agricultural and Food Chemistry, (2017) 65: 9087-9093.
25.Jingwen Yang, Bianca Pérez, Sampson Anankanbil, Jingbo Li, Renjun Gao*, Zheng Guo*, Enhanced Synthesis of Alkyl Galactopyranoside by Thermotoga naphthophila β-Galactosidase Catalyzed Transglycosylation: Kinetic Insight of a Functionalized Ionic Liquid-Mediated System, ACS Sustainable Chemistry & Engineering, (2017) 5: 2006-2014.
26.Jingwen Yang, Xiaochen Chen, Dahai Yu, Renjun Gao*, Microwave-assisted synthesis of butyl galactopyranoside catalyzed by β-galactosidase from thermotoga naphthophila RKU-10, Process Biochemistry, (2016) 51: 53-58.
27.Jingwen Yang, Xiangjun Di, Man Wang, Renjun Gao*, Gene Clone and Characterization of a Novel Thermostable β-Galactosidase with Transglycosylation Activity from Thermotoga naphthophila RUK-10, Chemical Research in Chinese Universities, (2015) 31: 564-568.
专利：
1.杨静文;胡超;张洪斌. 一种纤维二糖差向异构酶突变体及其应用. 中国. 2025年09月12日. 专利号：ZL 2024 1 1599562.2
