Deyan Gong
Title: Associate Professor
Department: Department of Pharmaceutical Science and Engineering
Email: gongdy@hfut.edu.cn
Personal Introduction
Joined the School of Food and Biological Engineering, Hefei University of Technology in January 2021. Holded a PhD from the School of Chemistry and Chemical Engineering, Lanzhou University, and was a joint doctoral candidate in the Department of Chemistry at the University of Chicago (funded by the China Scholarship Council). Primarily engaged in research on the biomedical effects of nanomedicine and imaging diagnosis and treatment of major diseases such as liver disease, intestinal disease, and cancer. Has led multiple scientific research projects, including the Youth Project of National Natural Science Foundation of China and the Youth Project of Anhui Provincial Natural Science Foundation, and has published over 30 high-quality papers.
Research Fields:
1. Biological Imaging Nanomedicines 2. Liver and Intestinal Inflammation Diagnosis and Treatment Nanomedicines 3. Tumor Imaging Diagnosis and Treatment Nanomedicines
Representative Papers
1.Xiang Ling#, Deyan Gong#, Wenjie Shi, Ziwan Xu, Wenbo Han, Guangxu Lan, Youyou Li, Wenwu Qin, Wenbin Lin*, Nanoscale Metal−Organic Layers Detect Mitochondrial Dysregulation and Chemoresistance via Ratiometric Sensing of Glutathione and pH, Journal of the American Chemical Society, 2021, 143(3): 1284-1289.
2.Deyan Gong, Yuejun Tian, Chengduan Yang, Anam Iqbal, Zhiping Wang, Weisheng Liu, Wenwu Qin*, Xiangtao Zhu, Huichen Guo*, A fluorescence enhancement probe based on BODIPY for the discrimination of cysteine from homocysteine and glutathione [J]. Biosensors and Bioelectronics, 2016, 85, 178-183.
3. Deyan Gong, Xiangtao Zhu, Yuejun Tian, Shi-Chong Han, Min Deng, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, A Phenylselenium-Substituted BODIPY Fluorescent Turn-off Probe for Fluorescence Imaging of Hydrogen Sulfide in Living Cells [J]. Analytical Chemistry, 2017, 89, 1801−1807.
4. Deyan Gong, Shi-Chong Han, Anam Iqbal, Jing Qian, Ting Cao, Wei Liu, Weisheng Liu, Wenwu Qin*, and Huichen Guo*, Fast and Selective Two-Stage Ratiometric Fluorescent Probes for Imaging of Glutathione in Living Cells [J]. Analytical Chemistry, 2017, 89, 13112−13119.
5. Deyan Gong, Ting Cao, Shi-Chong Han, Xiangtao Zhu, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, Fluorescence enhancement thermoresponsive polymer luminescent sensors based on BODIPY for intracellular temperature [J]. Sensors and Actuators B: Chemical, 2017, 252, 577–583.
6. Deyan Gong, Jiaxi Ru, Ting Cao, Jing Qian, Wei Liu, Anam Iqbal, Weisheng Liu, Wenwu Qin*, Huichen Guo*, Two-stage ratiometric fluorescent responsive probe for rapid glutathione detection based on BODIPY thiol-halogen nucleophilic mono- or disubstitution [J]. Sensors and Actuators B: Chemical, 2018, 258, 72–79.
7. Zineng Yi, Xiaona Xu, Xiaohan Meng, Congyu Liu, Qianpeng Zhou, Deyan Gong*, Zhengbao Zha*, Emerging markers for antimicrobial resistance monitoring [J]. Chinese Chemical Letters, 2023, 34(10): 108238.
8. Deyan Gong#, Ziwen Xiao#, Yaoyu Hu, Silong Wu, Zineng Yi, Taikui Sheng, Zhengbao Zha, Yan Ma*, Zhaohua Miao*, Neutrophil elastase-activated carbon dots for non-invasive early diagnosis of inflammatory bowel disease by near-infrared-II fluorescence imaging, Chemical Engineering Journal, 2024, 499: 156099.
9. Deyan Gong#, Lu Liu#, Ziwen Xiao, Zhuonan Yang, Yaoyu Hu, Taikui Sheng, Yajing Liu*, Zhaohua Miao*, Zhengbao Zha*, pH-activated metal–organic layer nanozyme for ferroptosis tumor therapy, Journal of Colloid and Interface Science 680 (2025) 937–947.
10. Ziwen Xiao, Yu Liu, Zhenchao Tao, Yu Zhang, Qian Chen, Zhaohua Miao, Zhengbao Zha, Yan Ma*, Hua Wang*, Deyan Gong*. Tungsten disulfide atomic crystals with RONS scavenging and liver targeting capabilities for acetaminophen-induced acute liver injury therapy. Journal of Nanobiotechnology 23, 665 (2025).
11. Yu Liu, Ziwen Xiao, Yu Zhang, Qian Chen, Siyu Luo, Yaoqing Wang, Zhaohua Miao, Zhenchao Tao*, Deyan Gong*, Polypyrrole nanozymes with cell-free DNA scavenging and ferroptosis inhibition capabilities for the treatment of acetaminophen-induced acute liver injury, Acta Biomaterialia, 215 (2026) 215-227.
