讲师/助理研究员
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徐建国
发布时间:2018-09-11    阅读次数: 1060
姓 名:
徐建国
职 称:
讲师
职 务:
 
所属系:
食品科学与工程系
邮 箱:
jgxu0816@163.comjgxu-sfse@hfut.edu.cn
电 话:
 
个人学习工作简介

20176-至今:          合肥工业大学,讲师

20129-20176月:福州大学,生物化工,硕博连读

20089-20126月:阜阳师范大学,材料化学,学士
主要研究领域与方向
食品安全危害物、疾病标志物增敏分析检测
目前承担的科研项目

1.国家自然科学基金青年科学基金,2019.01-2021.12,主持

2.安徽省重点研发计划项目,2020.01-2022.12主持

3.安徽省自然科学基金青年基金项目,2019.07-2021.06,主持

4.中国博士后科学基金面上项目,2019.06-2021.01,主持

5.国家重点实验室开放基金项目,2019.04-2021.03,主持(经费到校)

6.合肥工业大学学术新人提升B计划,2019.04-2020.12,主持

7.合肥工业大学学术新人提升A计划,2018.05-2019.12,主持(结题)

8.合肥工业大学科研启动基金,2017.06-2020.06,主持
代表研究成果

一、期刊论文(通讯作者和第一作者):

1)Wei Chen, Jun Teng, Li Yao, Jianguo Xu*, and Guodong Liu. Selection of specific DNA aptamers for hetero-sandwich based colorimetric determination of Campylobacter jejuni in food. Journal of Agricultural and Food Chemistry. DOI: 10.1021/acs.jafc.0c02865

2)Wei Chen*, Lijun Yang, Chao Yan, Bangben Yao, Jian-feng Lu, Jianguo Xu*, and Guodong Liu*. Surface-confined building of Au@Pt-centered and multi-G-quadruplex/hemin wires-surrounded electroactive supernanostructures for ultrasensitive monitoring of morphine. ACS Sensors. DOI: 10.1021/acssensors.0c01230

3)Prediction, evaluation, confirmation, and elimination of matrix effects for lateral flow test strip based rapid and on-site detection of aflatoxin B1 in tea. Wei Chen*, Fen Cai, Qian Wu, Yuhan Wu, Bangben Yao, and Jianguo Xu*. Food Chemistry. 2020, 328, 127081

4)Panzhu Qin, Li Yao,Jianguo Xu*, Guodong Liu, Wei Chen*. Smart engineering of a dual-DNA machine with a high signal-to-noise ratio for one-pot robust and sensitive miRNA signaling.Chemical Communications, 2019,55, 14367-14370

5)Jie Wang, Shuhui Li, Jianguo Xu*, Yusheng Lu, Min Lin, Chaihung Wang, Chen Zhang, Guoxing Lin, Lee Jia*. Functionalized dumbbell probe-based cascading exponential amplification DNA machine enables amplified probing of microRNAs. Chemical Communications, 2020, 56, 1681-1684

6)Jianguo Xu#, Chao Yan#, Xinxin Wang, Bangben Yao, Jianfeng Lu, Guodong Liu*, Wei Chen*. Ingenious design of DNA concatamers and G-quadruplex wires assisted assembly of multi-branched DNA nanoarchitectures for ultrasensitive biosensing of miRNA. Analytical Chemistry, 2019, 91: 9747-9753

7)Wei Chen, Chao Yan, Lin Cheng, Li Yao, Feng Xue,Jianguo Xu*. An ultrasensitive signal-on electrochemical aptasensor for ochratoxin A determination based on DNA controlled layer-by-layer assembly of dual gold nanoparticle conjugates, Biosensors and Bioelectronics, 2018,117: 845–851

8)Jianguo Xu, Zai-Sheng Wu*, Zhenmeng Wang, Jingqing Le, Tingting Zheng, Lee Jia*. Autonomous assembly of ordered metastable DNA nanoarchitecture and in situ visualizing of intracellular microRNAs, Biomaterials, 2017, 120: 57-65

9)Jianguo Xu, Zai-Sheng Wu*, Zhenmeng Wang, Hongling Li, Jingqing Le, and Lee Jia*, Two-wheel drive-based DNA nanomachine and its sensing potential for highly sensitive analysis of cancer-related gene, Biomaterials, 2016, 100: 110-117

10)Jianguo Xu, Hongling Li, Zai-Sheng Wu*, Jun Qian, Chang Xue, Lee Jia*. Double-stem hairpin probe and ultrasensitive colorimetric detection of cancer-related nucleic acids, Theranostics, 2016, 6: 318-327

11)Jianguo Xu, Zai-Sheng Wu*, Weiyu Shen, Jingqing Le, Tingting Zheng, Hongling Li, Lee Jia*. Programmable nanoassembly consisting of two hairpin-DNAs for p53 gene determination, Biosensors and Bioelectronics, 2017, 94: 626-631

12)Jianguo Xu, Zai-Sheng Wu*, Hongling Li, Zhenmeng Wang, Jingqing Le, Tingting Zheng, Lee Jia*. Dual-cyclical nucleic acid strand-displacement polymerization based signal amplification system for highly sensitive determination of p53 Gene, Biosensors and Bioelectronics, 2016, 86: 1024-1030

13)Jianguo Xu#, Jun Qian#, Hongling Li, Zai-Sheng Wu*, Weiyu Shen, Lee Jia*, Intelligent DNA machine for the ultrasensitive colorimetric detection of nucleic acids, Biosensors and Bioelectronics, 2016, 75: 41-47

14)Jianguo Xu, Haiyan Dong, Weiyu Shen, Sudan He, Hongling Li, Yusheng Lu, Zai-Sheng Wu*, Lee Jia*. New molecular beacon for p53 gene point mutation and significant potential in serving as the polymerization primer, Biosensors and Bioelectronics, 2015, 66: 504-511

15)Jianguo Xu, Zai-Sheng Wu*, Weiyu Shen, Huo Xu, Hongling Li, Lee Jia*. Cascade DNA nanomachine and exponential amplification biosensing, Biosensors and Bioelectronics, 2015, 73: 19-25

16)Hongbo Li*, Mingbin Liu, Weihua Zhao, Jiamei Pu, Jianguo Xu*, Suqin Wang, Ruqin Yu*. Multi-channel collection of G-quadruplex transducers for amplified signaling of Pax-5 based on target-triggered split-to-intact remodeling of dual-G-rich duplex probe. Sensors & Actuators: B. Chemical, 2020, 311: 127913-127929

17)Xiaoming Ma, Shan He, Ying Zhang, Jianguo Xu*, Huifang Zhang, Zhen Wang, Jun Xue, Xun Li,* Wenbo Yu*. Xiaolin FanaSignal-off tuned signal-on (SF-T-SN) colorimetric immunoassay for amantadine using activity-metalmodulated peroxidase-mimicking nanozyme. Sensors & Actuators: B. Chemical, 2020, 311, 127933-127938

18)Jianguo Xu, Zai-Sheng Wu*, Yanru Chen, Tingting Zheng, Jingqing Le, Lee Jia*. Collapse of chain anadiplosis-structured DNA nanowires for highly sensitive colorimetric assay of nucleic acids, Analyst, 2017, 142: 613-620

19)Jianguo Xu#, Tingting Zheng#, Jingqing Le, Lee Jia*, Long-stem shaped multifunctional molecular beacon for highly sensitive nucleic acids determination via intramolecular and intermolecular interactions based strand displacement amplification, Analyst, 2017, 142: 4438–4445

20)Li Yao, Yulin Li, Kewen Cheng, Daodong Pan,Jianguo Xu*, Wei Chen*,Determination of 17β-estradiol by surface-enhanced Raman spectroscopy merged with hybridization chain reaction amplification on Au@Ag core-shell nanoparticles. Microchimica Acta, 2019, 186(2): 52.

21)Xiaoming Ma, Zhen Wang, Shan He, Jingyi Zhao, Xiaoqi Lai*, Jianguo Xu*. L-cysteine modified gold nanoparticles for tube-based fluorometric determination of mercury(II) ions. Microchimica Acta, 2019, 186(9): 632.

22)Jianguo Xu, Tingting Zheng, Jingqing Le, Lee Jia*, Stepwise nanoassembly of a single hairpin probe and its biosensing, Talanta, 2018, 187, 272-278

23)Panzhu Qin, Dongqing Qiao, Yan Gao, Li Yao, Jianfeng Lu, Jianguo Xu*, Wei Chen*. Self-signal-on fluorescent colorimetric protocol for rapid authentication of horsemeat adulterated beef samples with functional designed probes. International Journal of Food Science & Technology, 2019, 54(5): 1752-1759.

24)Panzhu Qin, Wei Qu, Jianguo Xu*, Dongqing Qiao, Li Yao, Feng Xue, Wei Chen*. A sensitive multiplex PCR protocol for simultaneous detection of chicken, duck, and pork in beef samples. Journal of food science and technology, 2019, 56(3): 1266-1274.

25)Wei Chen, Xinni Li, Qian Wu, Li Yao, Jianguo Xu*. Rapid and easy determination of morphine in chafing dish condiments with colloidal gold labeling based lateral flow strips. Food Science and Human Wellness, 2019, 8(1): 40-45.

26)Jianguo Xu*, Xinxin Wang, Chao Yan, Wei Chen*. A Polyamidoamine Dendrimer-Based Electrochemical Immunosensor for Label-Free Determination of Epithelial Cell Adhesion Molecule-Expressing Cancer Cells. Sensors, 2019, 19(8): 1879.

二、专著:

1)Jianguo Xu, Li Yao, Lin Cheng, Chao Yan, and Wei Chen*. “Development of Aptamer-Based Electrochemical Methods.” Aptamers for Analytical Applications: Affinity Acquisition and Method Design, Willey publishing, 2018: 247-271.

2)《食品安全学》,郑州大学出版社,编委,201912
获奖情况
 

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